Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid
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منابع مشابه
Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid
Background Mucociliary clearance is the main self-clearing system of the nasal cavity and paranasal sinuses.This is a very important means of non specific defence against continuous organic and inorganic contamination conveyed by air. It works by trapping particles and microorganisms in the mucus and then by transporting the mucous film to the pharynx where it is eliminated with a cough or swal...
متن کاملA viscoelastic traction layer model of muco-ciliary transport.
A new mathematical model of the transport of mucus and periciliary liquid (PCL) in the airways by cilia is presented. Mucus is represented by a linearly viscoelastic fluid, the mat of cilia is modelled as an 'active porous medium.' The propulsive effect of the cilia is modelled by a time-dependent force acting in a shear-thinned 'traction layer' between the mucus and the PCL. The effects of sur...
متن کاملEffect of Cilia Beat Frequency on Muco-ciliary Clearance
Background: The airway surface liquid (ASL), which is a ï‚uid layer coating the interior epithelial surface of the bronchi and bronchiolesis, plays an important defensive role against foreign particles and chemicals entering lungs.Objective: Numerical investigation has been employed to solve two-layer model consisting of mucus layer as a viscoelastic fluid and periciliary liquid layer as a New...
متن کامل1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid
THE TITLE COMPOUND [SYSTEMATIC NAME: 11-oxo-2,3-(oxy-dinitrilo)olean-12-en-29-oic acid], C(30)H(42)N(2)O(4), contains a linear array of five six-membered rings and a five-membered heterocyclic ring. The C ring, containing an α,β-unsaturated ketone, has a slightly distorted half-chair conformation, as does the A ring, with N-C-C angles 125.3 (5), 111.2 (4), 124.9 (5) and 109.2 (5)°, while the ot...
متن کاملMuco-ciliary differentiation of nasal epithelial cells is decreased after wound healing in vitro.
BACKGROUND Epithelial damage and modifications of cell differentiation are frequent in airway diseases with chronic inflammation, in which transforming growth factor-beta1 (TGF-beta1) plays an important role. The aim of this study was to evaluate the differentiation of human nasal epithelial cells (HNEC) after wound healing and the potential effects of TGF-beta1. METHODS Basal, mucus, and cil...
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ژورنال
عنوان ژورنال: Multidisciplinary Respiratory Medicine
سال: 2017
ISSN: 2049-6958
DOI: 10.1186/s40248-017-0110-7